How Crohn’s Disease and Colitis Impact Your Smile

Crohn's Disease Marielaina Perrone DDS

Crohn’s disease and ulcerative colitis, collectively known as inflammatory bowel diseases (IBD), are chronic gastrointestinal conditions affecting millions worldwide. These conditions can have widespread effects on the body, potentially impacting oral health. While the primary focus of managing Crohn’s disease and colitis is on gastrointestinal symptoms, it’s essential not to overlook the potential dental complications associated with these diseases. In this article, we’ll explore the relationship between Crohn’s disease, colitis, and oral health, understand the oral symptoms they may cause, and provide tips for maintaining a healthy smile while managing these challenging gastrointestinal conditions.

Understanding Crohn’s Disease and Ulcerative Colitis

Before diving into the oral health aspects, let’s briefly review Crohn’s disease and ulcerative colitis. 

Crohn’s disease is a chronic inflammatory condition affecting any part of the digestive tract, from the mouth to the anus. It leads to inflammation, ulcers, and other complications within the gastrointestinal tract, and its exact cause is unknown. Common symptoms include abdominal pain, diarrhea, weight loss, and fatigue.

On the other hand, Ulcerative colitis primarily affects the colon (large intestine) and rectum. It causes inflammation and ulcers in the colon’s lining and typically results in symptoms like bloody diarrhea, abdominal cramps, and frequent bowel movements.

The Oral Health Connection

While Crohn’s and colitis primarily affect the gastrointestinal tract, their systemic nature can impact other body parts, including the oral cavity. Here are some ways in which these conditions can affect your oral health:

  1. Mouth Ulcers: One of the most common oral symptoms associated with Crohn’s and colitis is the development of painful mouth ulcers or canker sores. These ulcers can occur on the gums, tongue, lips, and the inside of the cheeks. The exact cause of these ulcers is not fully understood, but inflammation and immune system dysfunction are believed to contribute.
  2. Gum Inflammation: Individuals with Crohn’s disease and colitis may experience gum inflammation, also known as gingivitis. Inflammation in the body can affect the gums, leading to redness, swelling, tenderness, and bleeding during brushing or flossing.
  3. Dry Mouth: Some medications used to manage Crohn’s disease and colitis, such as corticosteroids, can lead to dry mouth (xerostomia). A lack of saliva can increase the risk of cavities and gum disease, as saliva is crucial in neutralizing acids and maintaining oral health.
  4. Tooth Decay and Erosion: Frequent vomiting due to gastrointestinal symptoms or as a side effect of medications can expose teeth to stomach acids. Over time, these acids can lead to tooth enamel erosion and an increased risk of cavities.
  5. Nutritional Deficiencies: Malabsorption of nutrients is a common issue in individuals with Crohn’s and colitis. When essential vitamins and minerals are not properly absorbed, it can affect overall health, including oral health. Nutrient deficiencies can contribute to gum disease, mouth ulcers, and a weakened immune system.

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Managing Your Oral Health

While living with Crohn’s disease or ulcerative colitis presents unique challenges, it’s crucial to prioritize your oral health. Here are some tips to help you maintain a healthy smile:

  1. Communicate with Your Healthcare Team: Inform your gastroenterologist and Dr. Perrone about your Crohn’s or colitis diagnosis and any medications you are taking. Collaboration between your healthcare providers can ensure you receive comprehensive care.
  2. Practice Excellent Oral Hygiene: Brush your teeth at least twice daily and floss daily. Consider using an antimicrobial or fluoride mouthwash recommended by your dentist. Maintaining good oral hygiene is essential for preventing gum disease and cavities.
  3. Stay Hydrated: If you experience dry mouth, sip water throughout the day to help alleviate the symptoms. Avoid sugary or acidic beverages that can contribute to tooth decay.
  4. Monitor Your Diet: Since nutrient absorption may be compromised, pay attention to your diet. Eat a balanced diet rich in vitamins and minerals. Consider supplements if recommended by your healthcare provider.
  5. Regular Dental Check-Ups: Visit Dr. Perrone for regular check-ups and cleanings. These appointments are essential for detecting and addressing oral health issues early.
  6. Gentle Dental Care: If you have mouth ulcers, inform Dr. Perrone, who can provide gentle care and recommend over-the-counter or prescription treatments to ease discomfort.
  7. Medication Management: If you’re taking medications that may affect oral health, discuss this with Dr. Perrone. She can guide you in managing potential side effects.

Medications and Oral Health in Crohn’s Disease and Colitis Management

Managing Crohn’s disease and colitis often involves using various medications to control inflammation and promote overall systemic health. While these medications play a crucial role in management of deisease, it’s important to be aware of their potential impact on oral health. Here, we explore common medications used in Crohn’s disease and colitis treatment, their possible side effects on oral health, and strategies for mitigating associated risks.

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Common Medications in Crohn’s Disease and Colitis Treatment


    • Purpose: To reduce inflammation.
    • Potential Oral Health Impact: Increased risk of oral thrush (fungal infection), gum disease, and delayed wound healing.
    • Mitigation Strategies: Practice meticulous oral hygiene, including regular brushing, flossing, and antimicrobial mouthwash use. Routine dental check-ups are essential.

Immunomodulators (Azathioprine, Mercaptopurine):

    • Purpose: To suppress the immune system and reduce inflammation.
    • Potential Oral Health Impact: Increased susceptibility to infections, including oral infections.
    • Mitigation Strategies: Maintain good oral hygiene, promptly address any signs of infection, and communicate closely with gastroenterologists and dentists.

Biologics (Infliximab, Adalimumab, Vedolizumab):

    • Purpose: Target specific proteins to reduce inflammation.
    • Potential Oral Health Impact: Minimal direct impact, but vigilance is crucial due to the potential for compromised immunity.
    • Mitigation Strategies: Practice regular oral hygiene, promptly address any signs of infection, and inform healthcare providers about any oral symptoms.

Aminosalicylates (Mesalamine, Sulfasalazine):

    • Purpose: To reduce inflammation in the digestive tract.
    • Potential Oral Health Impact: Rare but potential for allergic reactions or alterations in taste.
    • Mitigation Strategies: Report any unusual taste experiences promptly. Regular dental check-ups are advised.


    • Purpose: To treat infections.
    • Potential Oral Health Impact: Disruption of the oral microbiota, increased risk of oral thrush.
    • Mitigation Strategies: Probiotics may help restore oral microbiota balance. Maintaining good oral hygiene is essential.


While Crohn’s disease and ulcerative colitis primarily affect the gastrointestinal tract, they can significantly affect oral health. Maintaining good oral hygiene, monitoring your diet, and collaborating with your healthcare team are crucial steps in preserving your smile while managing these challenging gastrointestinal conditions. By staying proactive and addressing oral health concerns, you can minimize the impact of Crohn’s and colitis on your teeth and gums, ensuring your overall well-being.

About Marielaina Perrone, DDS

Dr. Marielaina Perrone is a highly experienced dentist dedicated to providing quality dental care to her patients in Las Vegas and Henderson, NV. She has over two decades ofmarielaina perrone dds las vegas nv expertise and is committed to personalized treatment plans tailored to individual needs and preferences. Dr. Perrone’s compassionate approach creates a comfortable atmosphere for her patients, promoting oral health and overall well-being.

Dr. Perrone stays up-to-date with the latest advancements in dentistry and believes in continuing education to deliver the best possible care. Beyond her practice, she volunteers her time and expertise to charitable organizations in her community.